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Some general considerations to keep in mind during treatment with argatroban include the following:
- This medication is given by a continuous intravenous infusion (an "IV drip"). Extra doses ("boluses") can be given if necessary.
- You will be monitored closely, using blood tests, to make sure the dosage is appropriate.
- If you will be switched to warfarin (Coumadin®, Jantoven®), an oral anticoagulant, there will usually be a period of overlap when you will receive both medications. This overlap helps prevent blood clots, as the warfarin begins to work slowly.
The dose your healthcare provider recommends will vary, depending on several factors, including:
- Your weight
- The reason you are receiving argatroban
- Other medical conditions you may have
- How you respond to the medication.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
(Click Argatroban Dosage for more information.)
Just like any medicine, argatroban may cause side effects. However, not everyone who receives the drug will experience problems. Most people tolerate it quite well.
However, as with most similar medications, argatroban can cause serious bleeding, including potentially fatal internal bleeding.
Common side effects of argatroban include but are not limited to:
- Bleeding
- Fever
- Low blood pressure (hypotension)
- Diarrhea
- Chest pain.
(Click Argatroban Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by: Kristi Monson, PharmD
Last reviewed by: Kristi Monson, PharmD