How Does It Work?
This medication is a direct thrombin inhibitor. It works by inhibiting the actions of thrombin, a naturally occurring protein in the body. Thrombin encourages clot formation in several different ways. By inhibiting thrombin, argatroban
helps to prevent the formation of blood clots.
Like other "blood thinners," argatroban does not break down clots. Instead, it slows down clot formation, giving the body a chance to break down the clots naturally.
Is It Safe for Children to Use Argatroban?
Although argatroban has not been systematically studied in children, it has been used quite a bit in children, particularly in children with HIT. Your healthcare provider can discuss the risks and benefits of using argatroban for your child's unique situation.
Off-Label Uses for Argatroban
On occasion, a healthcare provider may recommend this medication for something other than the uses discussed in this article. This is called an "off-label
" use. For example, sometimes argatroban is prescribed off-label:
- During or right after a heart attack or stroke
- In people without HIT (who are not at risk for HIT).