Argatroban is made by several different manufacturers, including GlaxoSmithKline, Sandoz, Inc., and Eagle Pharmaceuticals, Inc. It is available as a generic product. Generic argatroban is available in one strength (1 mg per mL) and is sold in 125-mL and 50-mL vials. The argatroban made by GlaxoSmithKline is sold under a generic name, but is not a generic version.
Argatroban is a prescription medication used as an anticoagulant in people who cannot take heparin medications due to a condition known as heparin-induced thrombocytopenia (HIT). It belongs to a class of drugs known as direct thrombin inhibitors. It is given intravenously (by IV).
Argatroban is made by a few different manufacturers, including:
- Sandoz, Inc.
- Eagle Pharmaceuticals, Inc.
Interestingly, in the United States, GlaxoSmithKline sells argatroban under the generic name rather than a brand name, which is highly unusual. It is unclear why this was done. It is also unclear if GlaxoSmithKline's argatroban is protected from generic competition by any patents.
The patent for argatroban currently expires in June 2014. Normally, this would be the earliest predictable date that a generic version could become available. However, it is unclear if this is true for argatroban, for a few different reasons.
First, it is highly unusual that GlaxoSmithKline decided to market argatroban under a generic name. Initially, they had intended to use a brand name of Acova™; it is possible that the name choice was related to a patent issue.
Second, generic argatroban is already available, although not in the same strength as GlaxoSmithKline's argatroban.