Before beginning treatment with Arixtra, the amount of your dosage will be determined using several factors, such as your weight and the reason you are using this drug. This medication is given as an injection just under the skin once a day. Make sure to take Arixtra as prescribed. If you stop taking it too soon, you may be increasing your risk for serious problems.
An Introduction to Your Dosage of ArixtraThe dose of Arixtra® (fondaparinux sodium) your healthcare provider recommends will vary, depending on a number of factors, including:
- The reason you are taking Arixtra
- Your weight
- Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically instructs you to do so.
Arixtra Dosing for Preventing Deep Vein Thrombosis (DVT) ClotsThe standard dose of Arixtra for preventing blood clots in people undergoing abdominal (stomach) surgery, hip replacement surgery, knee replacement surgery, or hip fracture surgery is Arixtra 2.5 mg once daily. The first dose should be started no sooner than six to eight hours after surgery (starting it sooner increases the risk of bleeding). The typical length of treatment is five to nine days, although much longer courses (such as 24 days of treatment) are often recommended for people who have had hip fracture surgery.
Arixtra Dosing for Treating DVT and Pulmonary Embolism (PE) ClotsThe standard dosage of Arixtra for treating DVT or PE depends on weight, as follows:
- Less than 100 pounds -- Arixtra 5 mg once daily
- 110 to 220 pounds -- Arixtra 7.5 mg once daily
- Over 220 pounds -- Arixtra 10 mg once daily.
For DVT or PE treatment, most people will also be started on warfarin (Coumadin®, Jantoven®), as warfarin is usually preferred as the long-term treatment. Arixtra should be continued for at least five days after the warfarin is started and only after laboratory tests show that the warfarin is effectively working.