Arixtra is a prescription blood thinner approved for adults. The specific uses of Arixtra include the treatment and prevention of blood clots in people who are undergoing various surgeries, such as hip or knee replacement surgery. It works by slowing down clot formation, allowing the body to break down blood clots naturally. One possible off-label use includes preventing clots in people with cancer.
What Is Arixtra Used For?Arixtra® (fondaparinux sodium) is a prescription anticoagulant medication, commonly known as a "blood thinner."
Arixtra is approved to both treat and prevent blood clots deep inside the veins of the body, known medically as deep vein thrombosis (DVT). DVT clots typically occur in the legs or hips. It can be especially dangerous if the clot dislodges and travels to the lungs, where it may cause a pulmonary embolism (PE).
Specifically, Arixtra is approved to prevent DVT blood clots in people who are undergoing the following types of surgeries:
- Abdominal (stomach) surgery (for those who are at a high risk for blood clots)
- Hip fracture surgery (for a broken hip)
- Hip replacement surgery
- Knee replacement surgery.
Arixtra is also approved for use in combination with warfarin (Coumadin®, Jantoven®) to treat a DVT that has already happened. It can be used either in the hospital or outside of the hospital in people who have just had a DVT. However, if the more serious complication of a pulmonary embolism (PE) has occurred, Arixtra should be used only in the hospital.
When used in combination with warfarin to treat a DVT or PE, the purpose of Arixtra is to provide immediate and short-term anticoagulation while waiting for the warfarin to start working (it takes a few days for the warfarin to begin working adequately).