Are allergic to Arixtra, fondaparinux, or any of the inactive components used to make the medication. Your healthcare provider or pharmacist has a list of the inactive ingredients.
Have severe kidney impairment.
Have active, major bleeding.
Have bacterial endocarditis (a bacterial infection of the lining of the heart).
Have (or have ever had) low blood platelets in combination with a positive lab test for antiplatelet antibodies due to Arixtra (sometimes known as "fondaparinux-induced thrombocytopenia").
Weigh less than 110 pounds (for clot prevention only; this restriction does not apply for clot treatment).

Final Thoughts

There are a number of situations in which Arixtra should not be taken, as well as several precautions and warnings people should be aware of before starting the medication. However, it is possible that not all of these issues were discussed in this article. Therefore, talk with your healthcare provider about the specific precautions and warnings with Arixtra that may apply to you.

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD

Last reviewed by: Kristi Monson, PharmD

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