This type of arteriosclerosis affects the inside and middle layer of arteries and smaller arteries known as arterioles. The blood vessels most affected are those in the:
  • Spleen
  • Adrenal glands
  • Kidneys
  • Pancreas.
When arteriolosclerosis occurs in the kidneys, high blood pressure (also known as hypertension) can occur.

What Is Arteriosclerosis Obliterans?

Arteriosclerosis obliterans is the leading cause of narrowing or blockage of arteries in the arms, legs, and pelvis. Arteriosclerosis obliterans is caused by atherosclerosis, so it is more commonly known as atherosclerosis of the extremities or peripheral arterial disease (PAD).
Arteriosclerosis obliterans is the most common type of peripheral vascular disease, which is a group of conditions that affect the arteries and veins in the extremities (arms, legs, and pelvis).
If the arteries that supply these areas are affected by arteriosclerosis obliterans, he or she may experience symptoms that include:
  • Claudication (pain, ache, or cramping in the muscles that occurs during exercise but improves with rest)
  • Cold or numb feeling in the feet or toes, especially at night.
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Atherosclerosis Disease

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