Blood Home > Asclera Side Effects

In clinical studies that compared Asclera to another sclerosing agent and to a placebo, commonly reported side effects included various reactions at the injection site, from bruising to itching. Most people have no problems, however, and any side effects with Asclera are generally mild and easily treated. Serious reactions to watch for include signs of a stroke, an allergic reaction, or blood clots in the lungs.

An Introduction to Asclera Side Effects

Just like any medicine, Asclera™ (polidocanol) can cause side effects. However, not everyone who uses the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Asclera. Your healthcare provider can discuss a more complete list with you.)

Reported Side Effects of Asclera

Asclera has been studied thoroughly in clinical trials. In these studies, Asclera was compared to both another sclerosing agent (sodium tetradecyl sulfate) and to a placebo (an injection with no active ingredients). This way, it was possible to observe the side effects that occurred with Asclera and how they compared with side effects of sodium tetradecyl sulfate or the placebo.
In these studies, reported side effects of Asclera included:
  • Bruising at the injection site -- in up to 42 percent of people
  • Irritation at the injection site -- up to 41 percent
  • Discoloration at the injection site -- up to 38 percent
  • Injection site pain -- up to 24 percent
  • Injection site itching -- up to 19 percent
  • Injection site warmth -- up to 16 percent
  • New blood vessel growth -- up to 8 percent
  • Blood clots at the injection site -- up to 6 percent.
Blood clots at the injection site can usually be treated (if necessary) by making a small incision in the skin and draining the lumps of clotted blood. These blood clots are not usually dangerous, as they occur in surface blood vessels, not in deeper vessels.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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