Because Fragmin (dalteparin) passes through breast milk, the manufacturer of the drug recommends that women use this medication with caution while breastfeeding. However, Fragmin is generally considered safe to use while nursing, as the drug would most likely be inactivated in the digestive tract of the infant. Because each woman's situation is different, talk to your healthcare provider about the risks and benefits.
Is Taking Fragmin While Breastfeeding Safe?
Fragmin® (dalteparin sodium) passes through breast milk in humans. The manufacturer of Fragmin recommends that breastfeeding women use this medication with caution. However, this and other similar low-molecular-weight heparin medications are generally considered safe for use while breastfeeding.
More Information on Breastfeeding and Fragmin
Fragmin passes through breast milk in very low amounts. The small amounts of Fragmin that do make it through breast milk would most likely be inactivated in the digestive tract of the infant (this is why the drug cannot be taken by mouth and must be injected).
Most sources consider Fragmin compatible with breastfeeding. Fragmin or other low-molecular-weight heparin medications are commonly given to women (who used the drug during pregnancy) for a period of time after giving birth, as women are at a high risk for clots after delivery. No special precautions or monitoring of the infant are recommended.
Talking With Your Healthcare Provider
You should talk with your healthcare provider about breastfeeding and Fragmin. Each woman's situation is different, and you and your healthcare provider understand your situation best. After considering what you want and expect, as well as your current health situation, the two of you can make a shared decision that is right for you.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Fragmin [package insert]. Woodcliff Lake, NJ: Eisai, Inc.;2009 December.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 8th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2008.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed May 5, 2010.
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