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Common Side Effects

Rivaroxaban has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people taking rivaroxaban were documented and compared to those that occurred in a similar group of people taking enoxaparin (Lovenox®). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the group taking enoxaparin.
 
In these studies, common rivaroxaban side effects included:
 
  • Any bleeding (including both major and minor bleeding) -- in up to 28.3 percent of people
  • Elevated liver enzymes (found using a blood test) -- up to 6.6 percent
  • Elevated bilirubin levels (found using a blood test) -- up to 3.2 percent
  • Back pain -- up to 3.7 percent
  • Bleeding in the digestive tract (gastrointestinal bleeding) -- up to 3.1 percent 
  • Fluid leaking from in or around the surgical incision -- up to 2.8 percent
  • Itching -- up to 2.1 percent
  • Low blood platelets (found using a blood test) -- up to 2.6 percent.
 

Final Thoughts

You may experience some or none of the side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have problems with a medicine that you have never tried.
 
Therefore, make sure to let your healthcare provider know if you develop any side effects while taking rivaroxaban. Also, let your healthcare provider know if you develop something that "just does not seem right." While it may not be related to the medication, your healthcare provider will be able to diagnose and treat the problem.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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