Blood Home > What Is Rivaroxaban Used For?

How Does This Medicine Work?

Rivaroxaban works by inhibiting a clotting factor known as Factor Xa. It is more selective than heparin (including both unfractionated heparin and low-molecular-weight heparins), which inhibits other clotting factors in addition to Factor Xa. Rivaroxaban is not a heparin medication and does not affect blood platelets.
Like other "blood thinners," rivaroxaban does not break down clots. Instead, it slows down clot formation, giving the body a chance to break down the clots naturally.

Is It Safe for Children to Use Rivaroxaban?

Rivaroxaban is not approved for use in children, as it has not been adequately studied in this group. It is unknown if this medicine is safe or effective in children.

Is Rivaroxaban Used for Off-Label Reasons?

On occasion, healthcare providers may recommend medications for something other than the approved uses. This is known as an "off-label" use. Some off-label uses for rivaroxaban include the following:
  • Preventing death or future heart attacks after certain cardiac events, such as heart attacks
  • "Bridge therapy" in people who must temporarily stop taking warfarin (Coumadin®, Jantoven®)
  • Preventing DVT after moderate-risk general surgeries
  • Preventing DVT after gynecological surgery or abdominal (stomach) surgery
  • Preventing DVT in people with cancer.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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