Nascobal nasal spray is prescribed to help maintain vitamin B12 levels. This medicine is specifically designed for people who have pernicious anemia, which occurs when vitamin B12 levels are not high enough for the body to make enough red blood cells. It can also be used as a supplement for people who have a vitamin B12 deficiency. Nascobal is approved for use in adults only.
What Is Nascobal Used For?Nascobal® (cyanocobalamin nasal spray) is a prescription nasal spray that contains cyanocobalamin, a form of vitamin B12. It is approved to maintain adequate vitamin B12 levels in people with pernicious anemia. It is also approved for use as a vitamin B12 supplement in certain other people who have vitamin B12 deficiencies.
Nascobal Use for Pernicious AnemiaVitamin B12 is important for healthy nerves and blood cells. Pernicious anemia is a type of anemia in which people cannot make enough red blood cells because they do not have enough vitamin B12. People with pernicious anemia usually cannot absorb enough vitamin B12 from food because they lack a protein known as intrinsic factor. Intrinsic factor, which is normally made by the cells that line the stomach, binds to vitamin B12 and helps the intestines absorb vitamin B12.
Red blood cells carry oxygen throughout the body. When red blood cells are depleted, the tissue and organs throughout the body cannot get the oxygen they need to work properly. As a result, people with anemia may tire easily, have difficulty concentrating, or feel weak, dizzy, or short of breath (see Anemia Symptoms for a list of other general signs of anemia).
Vitamin B12 deficiency can also lead to nerve damage, which may cause numbness, tingling, or other strange sensations in the hands or feet, problems with balance, and muscle weakness. If left untreated, nerve damage from vitamin B12 deficiency can become permanent.
Because people with pernicious anemia cannot properly absorb vitamin B12, the condition is often treated with vitamin B12 injections. These injections are usually given into a muscle (known as an intramuscular, or IM, injection). Nascobal is approved to maintain normal levels of vitamin B12 after successful treatment with injectable vitamin B12. It is meant for use in people who do not have signs of nerve damage from vitamin B12 deficiency.