When and How to Receive This Medicine

Some general considerations to keep in mind during treatment with pralatrexate include the following:
  • Pralatrexate comes as a liquid that is injected slowly into a vein (an intravenous, or IV, injection) once a week for six weeks, followed by a one-week break. The injection is normally given over three to five minutes.
  • The injection will be given by a healthcare provider in a healthcare setting, such as a hospital or clinic.
  • You will need to take folic acid and vitamin B12 during treatment to help prevent certain side effects.
  • Pralatrexate should be inspected before use and should not be used if it contains particles or is discolored.
  • For the medication to work properly, it must be used as prescribed. It is important to keep all of your appointments to receive your pralatrexate doses.

Dosing Information for Pralatrexate

The dose of pralatrexate your healthcare provider recommends will vary, based on a number of factors, including:
  • Your height and weight
  • How well you tolerate the medication.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
(Click Pralatrexate Dosage for more information.)

Drug Interactions

Pralatrexate may react with a number of other medicines (see Drug Interactions With Pralatrexate).

What If I Overdose on This Medicine?

An overdose of pralatrexate can be quite dangerous. Seek immediate medical attention if you believe you may have been given too much.
(Click Folotyn Overdose for more information.)
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Pralatrexate Drug Information

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