Treatments for Thalassemia (Cont.)

Iron Chelation Therapy as Treatment for Thalassemia

Iron chelation therapy uses medicine to remove the excess iron that builds up in the body when a person has regular blood transfusions. If the iron is not removed, it will damage organs such as the heart and liver.
 
The medication used for iron chelation is called deferoxamine. This medication works best when given slowly under the skin, usually with a small portable pump overnight. This treatment for thalassemia is demanding and sometimes mildly painful, which is why some people stop iron chelation therapy. A pill form of iron chelation therapy is being studied by thalassemia research scientists.
 
People who have iron overload should not take vitamins or other supplements that contain iron.
 

Surgical Treatments for Thalassemia

Surgery may be needed if organs such as the spleen or gallbladder are affected. For example, if the spleen becomes inflamed and enlarged, it may need to be removed. If gallstones develop, the gallbladder may need to be removed.
 

Bone Marrow and Stem Cell Transplants as Treatments for Thalassemia

Bone marrow or stem cell transplants have been used successfully in some children with severe thalassemia. Although bone marrow transplants offer a cure to some children, it is a risky procedure and it may result in death.
 

Other Treatments for Thalassemia

People with severe thalassemia are more likely to get infections that can make their anemia worse. Therefore, people living with thalassemia should get an annual flu shot and the pneumonia vaccine to help prevent infections. Also, taking folic acid supplements is important, as folic acid helps build red blood cells.

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Written by/reviewed by: Arthur Schoenstadt, MD
Last reviewed by: Arthur Schoenstadt, MD